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原发性肾病综合征患儿出生及发病时间的运气规律研究

The Study on the Wuyun LiuQi Rules Which Based on the Time of Birth and Onset of Children with Primary Nephritic Syndrome

作者: 专业:中医学(专业学位) 导师:黄清明 年度:2015 学位:硕士  院校: 广州中医药大学

Keywords

Children, Primary nephritic syndrome, WuYun LiuQi

        运气学说是一门古老而经典的学科。它借助“天人相应”的中医整体观作为学术核心指导思想,阴阳五行生克承制为基本理论,十天干十二地支作为运算推演的符号,以推测宇宙天象、自然界气象、物候以及人体正常的生理和疾病状态下的病理变化。通过挖掘自然现象和生物生命征象统一性,探求两者间的内在本质联系,它揭示了疾病的发病特性并提出与之相对应的预防治疗措施。历代以来,不少医家将其应用于临床医疗实践,指导疾病的预防和治疗,并取得重要成果。目的:本课题通过回顾性分析不同年龄组别原发性肾病综合征患儿出生及发病时间上的运气学差异,探讨该病的运气学规律,以期指导该病的临床诊治,同时为运气学说应用于小儿疾病研究积累经验。方法:收集2011年-2014年间广东省中医院儿科住院部原发性肾病综合征患儿117例,依发病年龄进行分组,根据患儿的出生及发病相关时间,按运气学理论推算其出生及发病时相关运气学指标,对数据进行统计分析,得出小儿原发性肾病综合征出生及发病的运气学特点,并比较不同年龄组别患儿出生及发病时间运气学规律差异性。结果:原发性肾病综合征患儿,多出生于岁运为金运太过、水运不及和土运不及之年,客气为太阴湿土所主之时;疾病好发于岁运为火运不及、水运不及和土运太过之年,客运为太水、太土所主之时。通过对相关指标进行组间分布差异性分析,发现出生岁运为金运太过在1-3岁组和4-7岁组两组患儿间分布有显著性差异;出生客运为少水在小于4岁(1-3岁组)和大于等于4岁(4-7岁组加8-14岁组)两组间分布有显著性差异;出生客气为少阳相火在1-3岁组和4-7岁组两组患儿间分布有显著性差异;发病客运中的少土在1-3岁组和4-7岁组两组患儿间分布有显著性差异。结论:本研究提示广东地区小儿肾病综合征的发病高峰为1-3岁;在出生及发病两方面,小儿原发性肾病综合征的全年龄段运气学规律与其中1-3岁组患儿的运气规律基本相似,同时不同年龄组别间患儿的运气学规律存在一定差异。根据研究结果,推测小儿原发性肾病综合征运气学相关气候特点以影响脾肾二脏功能为主,基本符合中医“同气相求”的疾病发病观,并推测原发性肾病综合征患儿多出生于天干为庚、辛、己年份,疾病好发于天干为癸、辛、甲年份。
    The doctrine on yunqi whose guiding ideology is "Heaven correspond-ding" holistic views and the base is the theory of Yin Yang and the five elements reinforced each other, is an ancient and classic subject to infer the changes of astronomy, meteorology, phenology, hominal physio-logy and pathology by the deduction tool of Chinese era. It summarizes the unity and explores the rules between natural phenomenon and biological phenomena, therefore it not only reveals the disease incidence regularity but also provides thecorresponding prevention and treatment method. For a long time, a great deal of doctors have put it into clini-cal practice to guide the work of disease prevention and treatment, and they make significant achievements.ObjectiveThis study investigates the WuYun LiuQi rules of primary nephritic syndrome by retrospectively analysing the YunQi characteristics based on the time of birth and onset of children with this disease in different age groups, in order to guide the clinical diagnosis and treatment, while it also aims to accumulate research experiences about applying YunQi doctrine to pediatric diseases.Methods117 samples in this study are patients in pediatric inpatient department of Guangdong Province Traditional Chinese Medical Hospital during 2011-2014. They are divided into three groups by the time of onset. According to the deduction tool of Chinese era, We get the corresponding index of YunqQi doctrine based on their time of birth and onset. After finishing statistical analysis, on one hand we have concluded the WuYun LiuQi rules in terms of birth and onset of this disease, on the other hand, we have compared and found the differences o-f YunQi characteristics of children in different age groups.ResultsThe present study results show that the children with primary nephritic syndrome are mostly born in the year whose year evolutive phase is strong metal/weak water/weak earth and the keqi of taiyinshitu, while they usually are taken bad in the year of weak fire/weak water/strong earth and the keyun of strong water/strong earth.By analyzing related indicators between different groups, it’s found that there is significant difference between group 1-3 years old and group 4-7 years old in the birth year evolutive phase of strong metal, while there is obvious discrepancy in distribution between group less than 4 years old and group greater than or equal to 4 years old in the indicator of birth keyun of weak water. Besides, difference exists between group 1-3 years old and 4-7 years old in birth keqi of shaoyangxianghuo. When it comes to onset, there is statistical significant difference between group 1-3 years old and group 4-7 years old in the indicator of keyun of weak earth.ConclusionsAccording to this study, we have found that the incidence peak of children primary nephritic syndrome in Guangdong area is 1-3 years old. The WuYun LiuQi rules related to birth and onset of children primary nephritic syndrome are similar to the pediatric patients in the group of 1-3 years old, and statistical significant differences about specially appointed indicators of WuYun LiuQi exist between different groups. Based on the study results, there is a conclusion that the functions of Zang Fu spleen and kidney in the children with primary nephritic syndrome are mostly suffered by the especial climate of WuYun LiuQi. Overall, it meets the view of pathogenesis in Chinese medicine that "like draws to like" So we can conjecture that children with primary nephritic syndrome are mostly born in the year whose heavenly stem is geng/xin/ji, and that the disease often outbreaks in the year whose heavenly stem is gui/xin/jia.
        

原发性肾病综合征患儿出生及发病时间的运气规律研究

摘要3-4
ABSTRACT4-5
引言8-10
第一部分 运气学说概述10-19
    1.1 运气学说形成的依据10-13
        1.1.1 运气学说的理论依据及形成年代10-12
        1.1.2 运气学说的天文学依据12-13
    1.2 运气学说的发展历程13-14
        1.2.1 唐代王冰发掘并传承运气学说13
        1.2.2 两宋金元是运气学说盛行和发展时期13-14
        1.2.3 明清是运气学说理论系统化时期14
        1.2.4 清末民国是运气学说的冰河期14
        1.2.5 近现代运气学说重焕理性研究光辉14
    1.3 运气学说的基础理论14-16
        1.3.1 运气学说的哲学基础——阴阳五行14-15
        1.3.2 运气学说的理论基础——道气论15-16
    1.4 运气学说的研究概览16-19
        1.4.1 基础性研究16-17
        1.4.2 印证性研究17-18
        1.4.3 临床应用研究18-19
第二部分 课题研究19-30
    2.1 资料与方法19
        2.1.1 研究对象19
        2.1.2 研究方法19
    2.2 研究结果19-25
        2.2.1 出生运气资料20-22
        2.2.2 发病运气资料22-25
    2.3 讨论25-30
        2.3.1 出生运气资料分析26-28
        2.3.2 发病运气资料分析28
        2.3.3 结论28-29
        2.3.4 问题与展望29-30
结语30-31
参考文献31-33
附录33-34
在校期间发表论文34-35
致谢35
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